According to Sheila Snow and Mali Klein’s research, when the doctors
connected with the Resperin Corporation, they started working with
Essiac. Rene began to advise the dose of one fluid ounce diluted in two
ounces of warm water before going to bed.  [4] 

Depending on the exact
nature and severity of your condition, you may have to consider taking
Essiac at this dosage level for a period of up to two years, with ‘resting’
intervals of perhaps one week off in every four in order to stimulate
maximum efficacy of the tea. “It is our experience that the body seems
to resist Essiac at higher doses. Rene Caisse considered high doses a
complete waste of the remedy and risked the possibility of stimulating
over-detoxification crises.”  [5]

“Dosage as a remedy for cancer: Drink 1 fluid ounce (30ml) Essiac
once daily, diluted with 2 fluid ounces (60ml) of hot water. This
should be sipped (like any hot tea), preferably before bedtime and at
least two hours after eating. Food should not be eaten within one hour
of drinking the tea.”  [3]

“It is very important to use the dosage as recommended, which was
based on more than 54 years experience. Rene was very concerned
about this, which is why she personally administered the dose to her
patients. The herbs are very potent, and in particular, Sheep Sorrel can
have the effect of enlarging the tumor too quickly, so that it may burst,
or a vital organ cay be blocked because of its increase in size.
Sometimes the tumors will soften, dissolve into small pieces and be
eliminated through the bowel or the urinary tract. Cancer growths in
the breast have been known to become encapsulated within six weeks
to three months, and can then be removed surgically with little danger
of metastasizing in the future. Cancers of the esophagus have also
become encapsulated and removed cleanly and safely by surgery.”  [3]

“In the first years of my research I found that some people experience
nausea and vomiting when the decoction is too strong, even after it has
been diluted with twice the volume of water….I started working with a
useful ‘middle way’ ratio, using 10 g. mixed herbs to 1 litre of water,
which translates to one fluid ounce measure of the dried herbs to 35
fluid ounces of water….This ratio has worked very well in application,
with no adverse side effects, and is well tolerated over a long period of
time with occasional rest periods and the option of doubling the dose
when necessary.”  [6]

Depending on special circumstances, very occasionally in her later
years, she would sometimes advise an initial dose of one fluid ounce
twice daily for the first five, ten or (rarely) thirty days before reducing
to one fluid ounce a day. Rene was always very particular about this
because she was aware that sometimes, when patients first began
taking the Essiac formula, their tumors might enlarge suddenly as
though they were gathering back the cancerous cells that had
metastasized. When that happened, she either gave lighter doses or
stopped treatment altogether for a time, to prevent a vital organ from
becoming blocked. It all depended on the nature and position of the
tumor. For example, primary brain tumors rarely metastasize and we
have had no reports of this type of swelling when taking Essiac in
these cases.